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-Structure paper
Title | Synthesis, improved antisense activity and structural rationale for the divergent RNA affinities of 3'-fluoro hexitol nucleic acid (FHNA and Ara-FHNA) modified oligonucleotides. |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 133, Page 16642-16649, Year 2011 |
Publish date | Dec 30, 2010 (structure data deposition date) |
Authors | Egli, M. / Pallan, P.S. / Allerson, C.R. / Prakash, T.P. / Berdeja, A. / Yu, J. / Lee, S. / Watt, A. / Gaus, H. / Bhat, B. ...Egli, M. / Pallan, P.S. / Allerson, C.R. / Prakash, T.P. / Berdeja, A. / Yu, J. / Lee, S. / Watt, A. / Gaus, H. / Bhat, B. / Swayze, E.E. / Seth, P.P. |
External links | J. Am. Chem. Soc. / PubMed:21919455 |
Methods | X-ray diffraction |
Resolution | 1.56 Å |
Structure data | PDB-3q61: |
Chemicals | ChemComp-HOH: |
Keywords | DNA / A-FORM DNA / 3'-Fluoro Hexitol Nucleic Acid / FHNA / Antisense oligonucleotides |