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-Structure paper
Title | Design, Synthesis, and X-ray Crystallographic Analysis of a Novel Class of HIV-1 Protease Inhibitors. |
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Journal, issue, pages | J. Med. Chem., Vol. 54, Page 7176-7183, Year 2011 |
Publish date | Aug 18, 2011 (structure data deposition date) |
Authors | Ganguly, A.K. / Alluri, S.S. / Caroccia, D. / Biswas, D. / Wang, C.H. / Kang, E. / Zhang, Y. / McPhail, A.T. / Carroll, S.S. / Burlein, C. ...Ganguly, A.K. / Alluri, S.S. / Caroccia, D. / Biswas, D. / Wang, C.H. / Kang, E. / Zhang, Y. / McPhail, A.T. / Carroll, S.S. / Burlein, C. / Munshi, V. / Orth, P. / Strickland, C. |
External links | J. Med. Chem. / PubMed:21916489 |
Methods | X-ray diffraction |
Resolution | 1.34 Å |
Structure data | PDB-3th9: |
Chemicals | ChemComp-9Y9: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / enzyme inhibition / aspartic protease / HIV/AIDS / conformational change / Amprenavir / HYDROLASE / HYDROLASE-HYDROLASE INHIBITOR complex |