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Structure paper

TitleThe Biological Buffer Bicarbonate/CO(2) Potentiates H(2)O(2)-Mediated Inactivation of Protein Tyrosine Phosphatases.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 133, Page 15803-15805, Year 2011
Publish dateJun 27, 2011 (structure data deposition date)
AuthorsZhou, H. / Singh, H. / Parsons, Z.D. / Lewis, S.M. / Bhattacharya, S. / Seiner, D.R. / Labutti, J.N. / Reilly, T.J. / Tanner, J.J. / Gates, K.S.
External linksJ. Am. Chem. Soc. / PubMed:21913686
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-3sme:
Structure of PTP1B inactivated by H2O2/bicarbonate
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / SULFENYL AMIDE BOND BETWEEN CYS 215 and SER 216

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