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TitleBinding and inhibition of human spermidine synthase by decarboxylated S-adenosylhomocysteine.
Journal, issue, pagesProtein Sci., Vol. 20, Page 1836-1844, Year 2011
Publish dateMay 8, 2011 (structure data deposition date)
AuthorsSeckute, J. / McCloskey, D.E. / Thomas, H.J. / Secrist, J.A. / Pegg, A.E. / Ealick, S.E.
External linksProtein Sci. / PubMed:21898642
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-3rw9:
Crystal Structure of human Spermidine Synthase in Complex with decarboxylated S-adenosylhomocysteine
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-DSH:
5'-S-(3-aminopropyl)-5'-thioadenosine

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / aminopropyltransferase

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