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Structure paper

TitleReactibodies Generated by Kinetic Selection Couple Chemical Reactivity with Favorable Protein Dynamics.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 108, Page 15954-, Year 2011
Publish dateNov 24, 2010 (structure data deposition date)
AuthorsSmirnov, I. / Carletti, E. / Kurkova, I. / Nachon, F. / Nicolet, Y. / Mitkevich, V.A. / Debat, H. / Avalle, B. / Belogurov, A.A. / Kuznetsov, N. ...Smirnov, I. / Carletti, E. / Kurkova, I. / Nachon, F. / Nicolet, Y. / Mitkevich, V.A. / Debat, H. / Avalle, B. / Belogurov, A.A. / Kuznetsov, N. / Reshetnyak, A. / Masson, P. / Tonevitsky, A.G. / Ponomarenko, N. / Makarov, A.A. / Friboulet, A. / Tramontano, A. / Gabibov, A.
External linksProc. Natl. Acad. Sci. USA / PubMed:21896761
MethodsX-ray diffraction
Resolution1.36 - 1.5 Å
Structure data

PDB-2xza:
Crystal Structure of recombinant A.17 antibody FAB fragment
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

PDB-2xzc:
Crystal Structure of phosphonate-modified recombinant A.17 antibody FAB fragment
Method: X-RAY DIFFRACTION / Resolution: 1.36 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

ChemComp-XOP:
8-METHYL-8-AZABICYCLO[3.2.1]OCTAN-3-YL PHENYLPHOSPHONATE

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM

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