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Title | Inhibition of influenza virus replication via small molecules that induce the formation of higher-order nucleoprotein oligomers. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 108, Page 15366-15371, Year 2011 |
Publish date | Apr 25, 2011 (structure data deposition date) |
Authors | Gerritz, S.W. / Cianci, C. / Kim, S. / Pearce, B.C. / Deminie, C. / Discotto, L. / McAuliffe, B. / Minassian, B.F. / Shi, S. / Zhu, S. ...Gerritz, S.W. / Cianci, C. / Kim, S. / Pearce, B.C. / Deminie, C. / Discotto, L. / McAuliffe, B. / Minassian, B.F. / Shi, S. / Zhu, S. / Zhai, W. / Pendri, A. / Li, G. / Poss, M.A. / Edavettal, S. / McDonnell, P.A. / Lewis, H.A. / Maskos, K. / Mortl, M. / Kiefersauer, R. / Steinbacher, S. / Baldwin, E.T. / Metzler, W. / Bryson, J. / Healy, M.D. / Philip, T. / Zoeckler, M. / Schartman, R. / Sinz, M. / Leyva-Grado, V.H. / Hoffmann, H.H. / Langley, D.R. / Meanwell, N.A. / Krystal, M. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:21896751 |
Methods | X-ray diffraction |
Resolution | 2.66 Å |
Structure data | PDB-3ro5: |
Chemicals | ChemComp-LGH: ChemComp-HOH: |
Source |
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Keywords | VIRAL PROTEIN / Influenza nucleoprotein |