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Title | Design and Synthesis of Inhaled P38 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease. |
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Journal, issue, pages | J. Med. Chem., Vol. 54, Page 7797-, Year 2011 |
Publish date | May 16, 2011 (structure data deposition date) |
Authors | Millan, D.S. / Bunnage, M.E. / Burrows, J.L. / Butcher, K.J. / Dodd, P.G. / Evans, T.J. / Fairman, D.A. / Hughes, S.J. / Kilty, I.C. / Lemaitre, A. ...Millan, D.S. / Bunnage, M.E. / Burrows, J.L. / Butcher, K.J. / Dodd, P.G. / Evans, T.J. / Fairman, D.A. / Hughes, S.J. / Kilty, I.C. / Lemaitre, A. / Lewthwaite, R.A. / Mahnke, A. / Mathias, J.P. / Philip, J. / Smith, R.T. / Stefaniak, M.H. / Yeadon, M. / Phillips, C. |
External links | J. Med. Chem. / PubMed:21888439 |
Methods | X-ray diffraction |
Resolution | 2 - 2.3 Å |
Structure data | PDB-2yis: PDB-2yiw: PDB-2yix: |
Chemicals | ChemComp-YIS: ChemComp-I46: ChemComp-HOH: ChemComp-YIW: ChemComp-YIX: |
Source |
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Keywords | TRANSFERASE / INHIBITOR SBDD KINASE / CELL CYCLE / PHOSPHORYLATION / SERINE/THREONINE-PROTEIN KINASE |