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TitleAn autoinhibitory helix in the C-terminal region of phospholipase C-beta mediates Galphaq activation.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 18, Page 999-1005, Year 2011
Publish dateFeb 16, 2011 (structure data deposition date)
AuthorsLyon, A.M. / Tesmer, V.M. / Dhamsania, V.D. / Thal, D.M. / Gutierrez, J. / Chowdhury, S. / Suddala, K.C. / Northup, J.K. / Tesmer, J.J.
External linksNat. Struct. Mol. Biol. / PubMed:21822282
MethodsX-ray diffraction
Resolution2 - 3.2 Å
Structure data

PDB-3qr0:
Crystal Structure of S. officinalis PLC21
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-3qr1:
Crystal Structure of L. pealei PLC21
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • sepia officinalis (common cuttlefish)
  • loligo pealei (longfin inshore squid)
KeywordsHYDROLASE / PH domain / EF hand / C2 domain / TIM barrel domain / phospholipase / calcium binding / phospholipid binding / TIM barrel / lipase / signaling protein

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