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Structure paper

TitleCrystal Structure of Mycobacterium Tuberculosis Zinc-Dependent Metalloprotease-1 (Zmp1), a Metalloprotease Involved in Pathogenicity.
Journal, issue, pagesJ. Biol. Chem., Vol. 286, Page 32475-, Year 2011
Publish dateJul 19, 2011 (structure data deposition date)
AuthorsFerraris, D.M. / Sbardella, D. / Petrera, A. / Marini, S. / Amstutz, B. / Coletta, M. / Sander, P. / Rizzi, M.
External linksJ. Biol. Chem. / PubMed:21813647
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-3zuk:
CRYSTAL STRUCTURE OF MYCOBACTERIUM TUBERCULOSIS ZINC METALLOPROTEASE ZMP1 IN COMPLEX WITH INHIBITOR
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-RDF:
N-ALPHA-L-RHAMNOPYRANOSYLOXY(HYDROXYPHOSPHINYL)-L-LEUCYL-L-TRYPTOPHAN / inhibitor*YM

ChemComp-211:
2,2',2''-NITRILOTRIETHANOL

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-ACT:
ACETATE ION

ChemComp-SO4:
SULFATE ION

ChemComp-CL:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsHYDROLASE/INHIBITOR / HYDROLASE-INHIBITOR COMPLEX / PATHOGENICITY / PHAGOSOME MATURATION

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