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Structure paper

TitleThe Structure of CDK8/CycC Implicates Specificity in the CDK/Cyclin Family and Reveals Interaction with a Deep Pocket Binder.
Journal, issue, pagesJ. Mol. Biol., Vol. 412, Page 251-266, Year 2011
Publish dateApr 8, 2011 (structure data deposition date)
AuthorsSchneider, E.V. / Bottcher, J. / Blaesse, M. / Neumann, L. / Huber, R. / Maskos, K.
External linksJ. Mol. Biol. / PubMed:21806996
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-3rgf:
Crystal Structure of human CDK8/CycC
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-BAX:
4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE / inhibitor*YM

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / TRANSCRIPTION / protein kinase complex

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