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-Structure paper
Title | Activation of the human nuclear xenobiotic receptor PXR by the reverse transcriptase-targeted anti-HIV drug PNU-142721. |
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Journal, issue, pages | Protein Sci., Vol. 20, Page 1713-1719, Year 2011 |
Publish date | Mar 23, 2011 (structure data deposition date) |
Authors | Cheng, Y. / Redinbo, M.R. |
External links | Protein Sci. / PubMed:21805522 |
Methods | X-ray diffraction |
Resolution | 2.8 Å |
Structure data | PDB-3r8d: |
Chemicals | ChemComp-PNU: ChemComp-HOH: |
Source |
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Keywords | TRANSCRIPTION / nuclear receptor / PXR / xenobiotic / ligand binding domain / Transcription regulation / xenobiotics / endobiotics |