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-Structure paper
| Title | Discovery of GSK1997132B a novel centrally penetrant benzimidazole PPARgamma partial agonist. |
|---|---|
| Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 21, Page 5568-5572, Year 2011 |
| Publish date | Jun 2, 2011 (structure data deposition date) |
Authors | Sime, M. / Allan, A.C. / Chapman, P. / Fieldhouse, C. / Giblin, G.M. / Healy, M.P. / Lambert, M.H. / Leesnitzer, L.M. / Lewis, A. / Merrihew, R.V. ...Sime, M. / Allan, A.C. / Chapman, P. / Fieldhouse, C. / Giblin, G.M. / Healy, M.P. / Lambert, M.H. / Leesnitzer, L.M. / Lewis, A. / Merrihew, R.V. / Rutter, R.A. / Sasse, R. / Shearer, B.G. / Wilson, T.M. / Xu, R.X. / Virley, D.J. |
External links | Bioorg. Med. Chem. Lett. / PubMed:21798739 |
| Methods | X-ray diffraction |
| Resolution | 2.55 Å |
| Structure data | ![]() PDB-3s9s: |
| Chemicals | ![]() ChemComp-M0T: ![]() ChemComp-HOH: |
| Source |
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Keywords | TRANSCRIPTION / PPAR / NUCLEAR RECEPTOR |
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