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TitleMulti-Domain Conformational Selection Underlies Pre-Mrna Splicing Regulation by U2Af
Journal, issue, pagesNature, Vol. 475, Page 408-, Year 2011
Publish dateApr 26, 2011 (structure data deposition date)
AuthorsMackereth, C.D. / Madl, T. / Bonnal, S. / Simon, B. / Zanier, K. / Gasch, A. / Rybin, V. / Valcarcel, J. / Sattler, M.
External linksNature / PubMed:21753750
MethodsNMR (solution)
Structure data

PDB-2yh0:
Solution structure of the closed conformation of human U2AF65 tandem RRM1 and RRM2 domains
Method: SOLUTION NMR

PDB-2yh1:
Model of human U2AF65 tandem RRM1 and RRM2 domains with eight-site uridine binding
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / PRE-MRNA SPLICING / RNA BINDING PROTEIN / MRNA PROCESSING

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