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Structure paper

TitleEpigallocatechin-gallate suppresses tumorigenesis by directly targeting Pin1.
Journal, issue, pagesCancer Prev Res (Phila), Vol. 4, Page 1366-1377, Year 2011
Publish dateAug 30, 2010 (structure data deposition date)
AuthorsUrusova, D.V. / Shim, J.H. / Kim, D.J. / Jung, S.K. / Zykova, T.A. / Carper, A. / Bode, A.M. / Dong, Z.
External linksCancer Prev Res (Phila) / PubMed:21750208
MethodsX-ray diffraction
Resolution1.89 Å
Structure data

PDB-3oob:
Structural and functional insights of directly targeting Pin1 by Epigallocatechin-3-gallate
Method: X-RAY DIFFRACTION / Resolution: 1.89 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-PE4:
2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL / precipitant*YM

ChemComp-KDH:
(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsISOMERASE / WW domain-like peptidyl prolyl isomerase / phosphorylation-dependent cis/trans isomerase / proteins with pSer/pThr-Pro motif

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