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-Structure paper
| Title | A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells. |
|---|---|
| Journal, issue, pages | Nat. Chem. Biol., Vol. 7, Page 566-574, Year 2011 |
| Publish date | Apr 15, 2011 (structure data deposition date) |
 Authors | Vedadi, M. / Barsyte-Lovejoy, D. / Liu, F. / Rival-Gervier, S. / Allali-Hassani, A. / Labrie, V. / Wigle, T.J. / Dimaggio, P.A. / Wasney, G.A. / Siarheyeva, A. ...Vedadi, M. / Barsyte-Lovejoy, D. / Liu, F. / Rival-Gervier, S. / Allali-Hassani, A. / Labrie, V. / Wigle, T.J. / Dimaggio, P.A. / Wasney, G.A. / Siarheyeva, A. / Dong, A. / Tempel, W. / Wang, S.C. / Chen, X. / Chau, I. / Mangano, T.J. / Huang, X.P. / Simpson, C.D. / Pattenden, S.G. / Norris, J.L. / Kireev, D.B. / Tripathy, A. / Edwards, A. / Roth, B.L. / Janzen, W.P. / Garcia, B.A. / Petronis, A. / Ellis, J. / Brown, P.J. / Frye, S.V. / Arrowsmith, C.H. / Jin, J. |
 External links | Nat. Chem. Biol. / PubMed:21743462 |
| Methods | X-ray diffraction |
| Resolution | 2.56 Å |
| Structure data |  PDB-3rjw: |
| Chemicals |  ChemComp-ZN:  ChemComp-SAH:  ChemComp-CIQ:  ChemComp-UNX:  ChemComp-HOH: |
| Source |
|
 Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / CHEMICAL PROBE / METHYLTRANSFERASE INHIBITOR / STRUCTURAL GENOMICS CONSORTIUM / SGC / TRANSFERASE-TRANSFERASE INHIBITOR complex |
homo sapiens (human)