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Structure paper

TitleStructural basis for the regulation of cysteine-protease activity by a new class of protease inhibitors in Plasmodium.
Journal, issue, pagesStructure, Vol. 19, Page 919-929, Year 2011
Publish dateNov 19, 2010 (structure data deposition date)
AuthorsHansen, G. / Heitmann, A. / Witt, T. / Li, H. / Jiang, H. / Shen, X. / Heussler, V.T. / Rennenberg, A. / Hilgenfeld, R.
External linksStructure / PubMed:21742259
MethodsX-ray diffraction
Resolution2.6 Å
Structure data

PDB-3pnr:
Structure of PbICP-C in complex with falcipain-2
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-CD:
Unknown entry

ChemComp-HOH:
WATER

Source
  • plasmodium falciparum (malaria parasite P. falciparum)
  • plasmodium berghei (eukaryote)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / Immunoglobulin fold / HYDROLASE-HYDROLASE INHIBITOR complex

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