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TitleIdentification of the allosteric regulatory site of insulysin.
Journal, issue, pagesPlos One, Vol. 6, Page e20864-e20864, Year 2011
Publish dateOct 12, 2010 (structure data deposition date)
AuthorsNoinaj, N. / Bhasin, S.K. / Song, E.S. / Scoggin, K.E. / Juliano, M.A. / Juliano, L. / Hersh, L.B. / Rodgers, D.W.
External linksPlos One / PubMed:21731629
MethodsX-ray diffraction
Resolution2.0776 - 2.1423 Å
Structure data

PDB-3p7l:
Rat Insulin Degrading Enzyme (Insulysin)
Method: X-RAY DIFFRACTION / Resolution: 2.0776 Å

PDB-3p7o:
Rat Insulin Degrading Enzyme (Insulysin) E111F mutant with two bound peptides
Method: X-RAY DIFFRACTION / Resolution: 2.1423 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • rattus norvegicus (Norway rat)
KeywordsHYDROLASE / peptidase / metallopeptidase

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