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Structure paper

TitleCrystal structure of plasminogen activator inhibitor-1 in an active conformation with normal thermodynamic stability.
Journal, issue, pagesJ. Biol. Chem., Vol. 286, Page 29709-29717, Year 2011
Publish dateDec 15, 2010 (structure data deposition date)
AuthorsJensen, J.K. / Thompson, L.C. / Bucci, J.C. / Nissen, P. / Gettins, P.G. / Peterson, C.B. / Andreasen, P.A. / Morth, J.P.
External linksJ. Biol. Chem. / PubMed:21697084
MethodsX-ray diffraction
Resolution2.3 - 2.6401 Å
Structure data

PDB-3q02:
Crystal structure of plasminogen activator inhibitor-1 in a metastable active conformation.
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3q03:
Crystal structure of plasminogen activator inhibitor-1 in a metastable active conformation.
Method: X-RAY DIFFRACTION / Resolution: 2.6401 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-ZN:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE INHIBITOR / PAI-1 / active serpin / serine protease inhibitor / metastable conformation

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