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TitleDiscovery of a novel class of 2-aminopyrimidines as CDK1 and CDK2 inhibitors
Journal, issue, pagesBioorg. Med. Chem. Lett., Vol. 21, Page 4203-4205, Year 2011
Publish dateMay 17, 2011 (structure data deposition date)
AuthorsLee, J. / Kim, K.-H. / Jeong, S.
External linksBioorg. Med. Chem. Lett. / PubMed:21684737
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-3s2p:
Crystal structure of CDK2 with a 2-aminopyrimidine compound
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-PMU:
(3S,4S)-1-{3-[2-amino-6-(propan-2-yl)pyrimidin-4-yl]-4-hydroxyphenyl}pyrrolidine-3,4-diol

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / protein kinase / transferase / Cell division protein kinase 2 / TRANSFERASE-TRANSFERASE INHIBITOR complex

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