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TitleNovel vinculin binding site of the IpaA invasin of Shigella.
Journal, issue, pagesJ. Biol. Chem., Vol. 286, Page 23214-23221, Year 2011
Publish dateApr 5, 2011 (structure data deposition date)
AuthorsPark, H. / Valencia-Gallardo, C. / Sharff, A. / Tran Van Nhieu, G. / Izard, T.
External linksJ. Biol. Chem. / PubMed:21525010
MethodsX-ray diffraction
Resolution1.61 Å
Structure data

PDB-3rf3:
Shigella IpaA-VBS3 in complex with human vinculin
Method: X-RAY DIFFRACTION / Resolution: 1.61 Å

Chemicals

ChemComp-CAC:
CACODYLATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • shigella flexneri (bacteria)
Keywordsprotein binding/toxin / alpha-helix bundle domain / cytoskeletal protein / protein-protein interactions / cell adhesion / cytoskeleton / bacterial toxins / pathogen-host interactions / IpaA / Talin / F-actin / phosphatidylinositol 4 5-bisphosphate / Cytosol / Focal adhesion / protein binding-toxin complex

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