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TitleStructural basis of defects in the sacsin HEPN domain responsible for autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS).
Journal, issue, pagesJ. Biol. Chem., Vol. 286, Page 20407-20412, Year 2011
Publish dateJul 20, 2010 (structure data deposition date)
AuthorsKozlov, G. / Denisov, A.Y. / Girard, M. / Dicaire, M.J. / Hamlin, J. / McPherson, P.S. / Brais, B. / Gehring, K.
External linksJ. Biol. Chem. / PubMed:21507954
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-3o10:
Crystal structure of the HEPN domain from human sacsin
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-MLI:
MALONATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCHAPERONE / all-helical domain / homodimerization

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