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Structure paper

TitleStructures of human exonuclease 1 DNA complexes suggest a unified mechanism for nuclease family.
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 145, Page 212-223, Year 2011
Publish dateJan 20, 2011 (structure data deposition date)
AuthorsOrans, J. / McSweeney, E.A. / Iyer, R.R. / Hast, M.A. / Hellinga, H.W. / Modrich, P. / Beese, L.S.
External linksCell(Cambridge,Mass. ) / PubMed:21496642
MethodsX-ray diffraction
Resolution2.51 - 3.1 Å
Structure data

PDB-3qe9:
Crystal structure of human exonuclease 1 Exo1 (D173A) in complex with DNA (complex I)
Method: X-RAY DIFFRACTION / Resolution: 2.51 Å

PDB-3qea:
Crystal structure of human exonuclease 1 Exo1 (WT) in complex with DNA (complex II)
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-3qeb:
Crystal structure of human exonuclease 1 Exo1 (WT) in complex with DNA and Mn2+ (complex III)
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-K:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-BA:
Unknown entry

ChemComp-MN:
Unknown entry

Source
  • homo sapiens (human)
KeywordsHYDROLASE/DNA / exonuclease / HYDROLASE-DNA complex

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