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TitleStructural analysis of 5'-mRNA-cap interactions with the human AGO2 MID domain.
Journal, issue, pagesEmbo Rep., Vol. 12, Page 415-420, Year 2011
Publish dateMar 1, 2011 (structure data deposition date)
AuthorsFrank, F. / Fabian, M.R. / Stepinski, J. / Jemielity, J. / Darzynkiewicz, E. / Sonenberg, N. / Nagar, B.
External linksEmbo Rep. / PubMed:21475248
MethodsX-ray diffraction
Resolution2 - 2.3 Å
Structure data

PDB-3qx8:
Crystal structure of MID domain from hAGO2 in complex with m7GpppG
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3qx9:
Crystal structure of MID domain from hAGO2 in complex with ATP
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-GTG:
7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE

ChemComp-HOH:
WATER

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

Source
  • homo sapiens (human)
KeywordsRNA BINDING PROTEIN / Rossmann-like folde / RNA binding / small RNA / Rossmann-like fold

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