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Structure paper

TitleInteraction of the P53 DNA-Binding Domain with its N-Terminal Extension Modulates the Stability of the P53 Tetramer.
Journal, issue, pagesJ. Mol. Biol., Vol. 409, Page 358-, Year 2011
Publish dateNov 4, 2010 (structure data deposition date)
AuthorsNatan, E. / Baloglu, C. / Pagel, K. / Freund, S.M. / Morgner, N. / Robinson, C.V. / Fersht, A.R. / Joerger, A.C.
External linksJ. Mol. Biol. / PubMed:21457718
MethodsX-ray diffraction
Resolution1.68 Å
Structure data

PDB-2xwr:
Crystal structure of the DNA-binding domain of human p53 with extended N terminus
Method: X-RAY DIFFRACTION / Resolution: 1.68 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCELL CYCLE / CANCER / TRANSCRIPTION FACTOR / APOPTOSIS

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