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TitleCardiolipin Binds to CD1d and Stimulates CD1d-Restricted {gamma}{delta} T Cells in the Normal Murine Repertoire.
Journal, issue, pagesJ. Immunol., Vol. 186, Page 4771-4781, Year 2011
Publish dateMar 23, 2010 (structure data deposition date)
AuthorsDieude, M. / Striegl, H. / Tyznik, A.J. / Wang, J. / Behar, S.M. / Piccirillo, C.A. / Levine, J.S. / Zajonc, D.M. / Rauch, J.
External linksJ. Immunol. / PubMed:21389252
MethodsX-ray diffraction
Resolution2.29 Å
Structure data

PDB-3ma7:
Crystal structure of Cardiolipin bound to mouse CD1D
Method: X-RAY DIFFRACTION / Resolution: 2.29 Å

Chemicals

ChemComp-CD4:
(2R,5R,11R,14R)-5,8,11-trihydroxy-5,11-dioxido-17-oxo-2,14-bis(tetradecanoyloxy)-4,6,10,12,16-pentaoxa-5,11-diphosphatriacont-1-yl tetradecanoate

ChemComp-PLM:
PALMITIC ACID

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / GAMMA DELTA T CELLS / GLYCOLIPID PRESENTATION / MHC / CD1 / CELL MEMBRANE / ENDOSOME / GLYCOPROTEIN / IMMUNE RESPONSE / IMMUNOGLOBULIN DOMAIN / INNATE IMMUNITY / LYSOSOME / MEMBRANE / TRANSMEMBRANE / MHC I / SECRETED / Disulfide bond / Immunity

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