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Structure paper

TitleA molecular basis for NKT cell recognition of CD1d-self-antigen
Journal, issue, pagesImmunity, Vol. 34, Page 315-326, Year 2011
Publish dateJan 28, 2011 (structure data deposition date)
AuthorsMallevaey, T. / Clarke, A.J. / Scott-Browne, J.P. / Young, M.H. / Roisman, L.C. / Pellicci, D.G. / Patel, O. / Vivian, J.P. / Matsuda, J.L. / McCluskey, J. ...Mallevaey, T. / Clarke, A.J. / Scott-Browne, J.P. / Young, M.H. / Roisman, L.C. / Pellicci, D.G. / Patel, O. / Vivian, J.P. / Matsuda, J.L. / McCluskey, J. / Godfrey, D.I. / Marrack, P. / Rossjohn, J. / Gapin, L.
External linksImmunity / PubMed:21376640
MethodsX-ray diffraction
Resolution2.3 - 2.5 Å
Structure data

PDB-3au1:
Crystal structure of mouse CD1d in complex with ganglioside GD3
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-3qi9:
Crystal structure of mouse CD1d-alpha-phosphotidylinositol with mouse Valpha14-Vbeta6 2A3-D NKT TCR
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-ERA:
(7Z,15E,17E)-N-[(2S,3S,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tricosa-7,15,17-trienamide

ChemComp-HOH:
WATER

ChemComp-PII:
2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE

ChemComp-MG:
Unknown entry

ChemComp-GOL:
GLYCEROL

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / immunoglobulin fold / antigen presenting molecule / T-cell receptor / cell surface protein with a single transmembrane domain / autoreactivity / T-cell surface

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