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TitleAn insertion mutation that distorts antibody binding site architecture enhances function of a human antibody.
Journal, issue, pagesMBio, Vol. 2, Page e00345-e00310, Year 2011
Publish dateJan 25, 2011 (structure data deposition date)
AuthorsKrause, J.C. / Ekiert, D.C. / Tumpey, T.M. / Smith, P.B. / Wilson, I.A. / Crowe, J.E.
External linksMBio / PubMed:21304166
MethodsX-ray diffraction
Resolution1.55 - 1.655 Å
Structure data

PDB-3qhf:
Crystal Structure of Fab del2D1, a deletion variant of anti-influenza antibody 2D1
Method: X-RAY DIFFRACTION / Resolution: 1.655 Å

PDB-3qhz:
Crystal Structure of human anti-influenza Fab 2D1
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Immunoglobulin / Immune recognition / Influenza A virus hemagglutinin / Extracellular (secreted) / Influenza A hemagglutinin

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