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TitleLoss of recognition by cross-reactive T cells and its relation to a C-terminus-induced conformational reorientation of an HLA-B*2705-bound peptide.
Journal, issue, pagesProtein Sci., Vol. 20, Page 278-290, Year 2011
Publish dateFeb 19, 2010 (structure data deposition date)
AuthorsLoll, B. / Ruckert, C. / Hee, C.S. / Saenger, W. / Uchanska-Ziegler, B. / Ziegler, A.
External linksProtein Sci. / PubMed:21280120
MethodsX-ray diffraction
Resolution1.94 Å
Structure data

PDB-3lv3:
Crystal structure of HLA-B*2705 complexed with a peptide derived from the human voltage-dependent calcium channel alpha1 subunit (residues 513-521)
Method: X-RAY DIFFRACTION / Resolution: 1.94 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / MHC (MAJOR HISTOCOMPATIBILITY COMPLEX) / HLA-B*2705 / Disulfide bond / Glycoprotein / Immune response / Membrane / MHC I / Transmembrane / Amyloid / Amyloidosis / Disease mutation / Glycation / Immunoglobulin domain / Secreted / Calcium channel / Voltage-gated channel

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