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Structure paper

TitleA single acidic residue can guide binding site selection but does not govern QacR cationic-drug affinity.
Journal, issue, pagesPlos One, Vol. 6, Page e15974-e15974, Year 2011
Publish dateNov 15, 2010 (structure data deposition date)
AuthorsPeters, K.M. / Brooks, B.E. / Schumacher, M.A. / Skurray, R.A. / Brennan, R.G. / Brown, M.H.
External linksPlos One / PubMed:21264225
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-3pm1:
Structure of QacR E90Q bound to Ethidium
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-ET:
ETHIDIUM

ChemComp-HOH:
WATER

Source
  • staphylococcus aureus (bacteria)
KeywordsTRANSCRIPTION / TetR family member / transcription regulation / multidrug resistance / DNA / nucleoid

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