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Structure paper

TitleStructure basis of bigelovin as a selective RXR agonist with a distinct binding mode
Journal, issue, pagesJ. Mol. Biol., Vol. 407, Page 13-20, Year 2011
Publish dateSep 25, 2010 (structure data deposition date)
AuthorsZhang, H. / Li, L. / Chen, L. / Hu, L. / Jiang, H. / Shen, X.
External linksJ. Mol. Biol. / PubMed:21262235
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-3ozj:
Crystal structure of human retinoic X receptor alpha complexed with bigelovin and coactivator SRC-1
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-BGV:
(3aR,4S,4aR,7aR,8R,9aS)-4a,8-dimethyl-3-methylidene-2,5-dioxo-2,3,3a,4,4a,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl acetate

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / nuclear receptor ligand-binding domain / ligand-binding and transactivation

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