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Structure paper

TitleCrystal Structure of the Tsh Receptor (Tshr) Bound to a Blocking-Type Tshr Autoantibody.
Journal, issue, pagesJ. Mol. Endocrinol., Vol. 46, Page 81-, Year 2011
Publish dateNov 5, 2010 (structure data deposition date)
AuthorsSanders, P. / Young, S. / Sanders, J. / Kabelis, K. / Baker, S. / Sullivan, A. / Evans, M. / Clark, J. / Wilmot, J. / Hu, X. ...Sanders, P. / Young, S. / Sanders, J. / Kabelis, K. / Baker, S. / Sullivan, A. / Evans, M. / Clark, J. / Wilmot, J. / Hu, X. / Roberts, E. / Powell, M. / Nunez Miguel, R. / Furmaniak, J. / Rees Smith, B.
External linksJ. Mol. Endocrinol. / PubMed:21247981
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-2xwt:
CRYSTAL STRUCTURE OF THE TSH RECEPTOR IN COMPLEX WITH A BLOCKING TYPE TSHR AUTOANTIBODY
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN/IMMUNE SYSTEM / SIGNALING PROTEIN-IMMUNE SYSTEM COMPLEX / GPCR / GRAVES' DISEASE / AUTOIMMUNITY / RECEPTOR-AUTOANTIBODY COMPLEX

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