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| Title | Structural basis for the cyclophilin A binding affinity and immunosuppressive potency of E-ISA247 (voclosporin). |
|---|---|
| Journal, issue, pages | Acta Crystallogr. ,Sect. D, Vol. 67, Page 119-123, Year 2011 |
| Publish date | Aug 11, 2010 (structure data deposition date) |
Authors | Kuglstatter, A. / Mueller, F. / Kusznir, E. / Gsell, B. / Stihle, M. / Thoma, R. / Benz, J. / Aspeslet, L. / Freitag, D. / Hennig, M. |
External links | Acta Crystallogr. ,Sect. D / PubMed:21245533 |
| Methods | X-ray diffraction |
| Resolution | 2.2 - 2.31 Å |
| Structure data | ![]() PDB-3odi: ![]() PDB-3odl: |
| Chemicals | ![]() ChemComp-HOH: |
| Source |
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Keywords | ISOMERASE/IMMUNOSUPPRESSANT / CALCINEURIN INHIBITION / CALCINEURIN / CYCLOSPORIN / PSORIASIS / IMMUNOSUPPRESSANT / VOCLOSPORIN / ISOMERASE-IMMUNOSUPPRESSANT COMPLEX |
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homo sapiens (human)
tolypocladium inflatum (fungus)
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