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Structure paper

TitleTuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 108, Page 598-602, Year 2011
Publish dateSep 24, 2009 (structure data deposition date)
AuthorsDerebe, M.G. / Sauer, D.B. / Zeng, W. / Alam, A. / Shi, N. / Jiang, Y.
External linksProc. Natl. Acad. Sci. USA / PubMed:21187421
MethodsX-ray diffraction
Resolution1.55 - 1.75 Å
Structure data

PDB-3k03:
Crystal Structure of CNG mimicking NaK mutant, NaK-DTPP, K+ complex
Method: X-RAY DIFFRACTION / Resolution: 1.62 Å

PDB-3ouf:
Structure of a K+ selective NaK mutant
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-3ous:
MthK channel pore T59A mutant
Method: X-RAY DIFFRACTION / Resolution: 1.75 Å

Chemicals

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-K:
Unknown entry

ChemComp-HOH:
WATER

Source
  • bacillus cereus (bacteria)
  • methanothermobacter thermautotrophicus (archaea)
KeywordsTRANSPORT PROTEIN / NaK-DTPP / DTPP / NaK / CNG mimicking / CNG channel selectivity filter / NaK-mutant / Ionic channel / MEMBRANE PROTEIN / Ion channel / membrane

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