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Structure paper

TitleHIV Capsid is a Tractable Target for Small Molecule Therapeutic Intervention.
Journal, issue, pagesPlos Pathog., Vol. 6, Page E1220-, Year 2010
Publish dateApr 30, 2010 (structure data deposition date)
AuthorsBlair, W.S. / Pickford, C. / Irving, S.L. / Brown, D.G. / Anderson, M. / Bazin, R. / Cao, J. / Ciaramella, G. / Isaacson, J. / Jackson, L. ...Blair, W.S. / Pickford, C. / Irving, S.L. / Brown, D.G. / Anderson, M. / Bazin, R. / Cao, J. / Ciaramella, G. / Isaacson, J. / Jackson, L. / Hunt, R. / Kjerrstrom, A. / Nieman, J. / Patick, A.K. / Perros, M. / Scott, A.D. / Whitby, K. / Wu, H. / Butler, S.L.
External linksPlos Pathog. / PubMed:21170360
MethodsX-ray diffraction
Resolution1.4 Å
Structure data

PDB-2xde:
Crystal structure of the complex of PF-3450074 with an engineered HIV capsid N terminal domain
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-1B0:
N-METHYL-NALPHA-[(2-METHYL-1H-INDOL-3-YL)ACETYL]-N-PHENYL-L-PHENYLALANINAMIDE

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus 1
KeywordsVIRAL PROTEIN / AIDS

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