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TitleConsequences of Cisplatin binding on nucleosome structure and dynamics.
Journal, issue, pagesChem. Biol., Vol. 17, Page 1334-1343, Year 2010
Publish dateJul 28, 2010 (structure data deposition date)
AuthorsTodd, R.C. / Lippard, S.J.
External linksChem. Biol. / PubMed:21168769
MethodsX-ray diffraction
Resolution3.216 Å
Structure data

PDB-3o62:
Nucleosome core particle modified with a cisplatin 1,3-cis-{Pt(NH3)2}2+-d(GpTpG) intrastrand cross-link
Method: X-RAY DIFFRACTION / Resolution: 3.216 Å

Chemicals

ChemComp-CPT:
Cisplatin / medication, chemotherapy*YM

Source
  • xenopus laevis (African clawed frog)
KeywordsSTRUCTURAL PROTEIN/DNA / nucleosome / cisplatin / STRUCTURAL PROTEIN-DNA complex

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