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-Structure paper
Title | Engineering a High Affinity Anti-Il-15 Antibody: Crystal Structure Reveals an Alpha-Helix in Vh Cdr3 as Key Component of Paratope. |
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Journal, issue, pages | J. Mol. Biol., Vol. 406, Page 160-, Year 2011 |
Publish date | Sep 1, 2010 (structure data deposition date) |
Authors | Lowe, D.C. / Gerhardt, S. / Ward, A. / Hargreaves, D. / Anderson, M. / Ferraro, F. / Pauptit, R.A. / Pattison, D.V. / Buchanan, C. / Popovic, B. ...Lowe, D.C. / Gerhardt, S. / Ward, A. / Hargreaves, D. / Anderson, M. / Ferraro, F. / Pauptit, R.A. / Pattison, D.V. / Buchanan, C. / Popovic, B. / Finch, D.K. / Wilkinson, T. / Sleeman, M. / Vaughan, T.J. / Mallinder, P.R. |
External links | J. Mol. Biol. / PubMed:21167836 |
Methods | X-ray diffraction |
Resolution | 2.6 Å |
Structure data | PDB-2xqb: |
Chemicals | ChemComp-SO4: ChemComp-HOH: |
Source |
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Keywords | IMMUNE SYSTEM / AFFINITY MATURATION |