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-Structure paper
| タイトル | Cryo-EM structure of the E. coli translating ribosome in complex with SRP and its receptor. |
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| ジャーナル・号・ページ | Nat Struct Mol Biol, Vol. 18, Issue 1, Page 88-90, Year 2011 |
| 掲載日 | 2010年12月12日 |
著者 | Leandro F Estrozi / Daniel Boehringer / Shu-Ou Shan / Nenad Ban / Christiane Schaffitzel / ![]() |
| PubMed 要旨 | We report the 'early' conformation of the Escherichia coli signal recognition particle (SRP) and its receptor FtsY bound to the translating ribosome, as determined by cryo-EM. FtsY binds to the ...We report the 'early' conformation of the Escherichia coli signal recognition particle (SRP) and its receptor FtsY bound to the translating ribosome, as determined by cryo-EM. FtsY binds to the tetraloop of the SRP RNA, whereas the NG domains of the SRP protein and FtsY interact weakly in this conformation. Our results suggest that optimal positioning of the SRP RNA tetraloop and the Ffh NG domain leads to FtsY recruitment. |
リンク | Nat Struct Mol Biol / PubMed:21151118 / PubMed Central |
| 手法 | EM (単粒子) |
| 解像度 | 13.5 Å |
| 構造データ | |
| 由来 |
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キーワード | PROTEIN TRANSPORT |
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