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Structure paper

TitleCrystal Structures of a Cysteine-Modified Mutant in Loop D of Acetylcholine Binding Protein
Journal, issue, pagesJ. Biol. Chem., Vol. 286, Page 4420-, Year 2011
Publish dateNov 23, 2010 (structure data deposition date)
AuthorsBrams, M. / Gay, E.A. / Colon Saez, J. / Guskov, A. / Van Elk, R. / Van Der Schors, R.C. / Peigneur, S. / Tytgat, J. / Strelkov, S.V. / Smit, A.B. ...Brams, M. / Gay, E.A. / Colon Saez, J. / Guskov, A. / Van Elk, R. / Van Der Schors, R.C. / Peigneur, S. / Tytgat, J. / Strelkov, S.V. / Smit, A.B. / Yakel, J.L. / Ulens, C.
External linksJ. Biol. Chem. / PubMed:21115477
MethodsX-ray diffraction
Resolution2.8 - 3.137 Å
Structure data

PDB-2xz5:
MMTS-modified Y53C mutant of Aplysia AChBP in complex with acetylcholine
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-2xz6:
MTSET-modified Y53C mutant of Aplysia AChBP
Method: X-RAY DIFFRACTION / Resolution: 3.137 Å

Chemicals

ChemComp-ACH:
ACETYLCHOLINE / neurotransmitter*YM

ChemComp-CL:
Unknown entry

ChemComp-PO4:
PHOSPHATE ION

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

ChemComp-ETM:
2-(TRIMETHYLAMMONIUM)ETHYL THIOL

Source
  • aplysia californica (California sea hare)
KeywordsRECEPTOR / AMIDATION / CONFORMATIONAL FLEXIBILITY / CONOTOXIN / NEUROTOXINNICOTINIC / POSTSYNAPTIC NEUROTOXIN / RECEPTOR/TOXIN

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