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TitleMechanism of Replication Blocking and Bypass of Y-Family Polymerase Eta by Bulky Acetylaminofluorene DNA Adducts.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 107, Page 20720-, Year 2010
Publish dateJun 7, 2010 (structure data deposition date)
AuthorsSchorr, S. / Schneider, S. / Lammens, K. / Hopfner, K.P. / Carell, T.
External linksProc. Natl. Acad. Sci. USA / PubMed:21076032
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-2xgp:
Yeast DNA polymerase eta in complex with C8-2-acetylaminofluorene containing DNA
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-2xgq:
Structure of yeast DNA polymerase eta in complex with C8-N-acetyl-2- aminoanthracene containing DNA
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsTRANSFERASE/DNA / TRANSFERASE-DNA COMPLEX / TRANSLESION DNA SYNTHESIS / DNA-BINDING / DNA DAMAGE

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