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TitleHinge-loop mutation can be used to control 3D domain swapping and amyloidogenesis of human cystatin C.
Journal, issue, pagesJ. Struct. Biol., Vol. 173, Page 406-413, Year 2011
Publish dateJul 12, 2010 (structure data deposition date)
AuthorsOrlikowska, M. / Jankowska, E. / Kolodziejczyk, R. / Jaskolski, M. / Szymanska, A.
External linksJ. Struct. Biol. / PubMed:21074623
MethodsX-ray diffraction
Resolution2.04 Å
Structure data

PDB-3nx0:
Hinge-loop mutation can be used to control 3D domain swapping and amyloidogenesis of human cystatin C
Method: X-RAY DIFFRACTION / Resolution: 2.04 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE INHIBITOR / cysteine protease inhibitor / 3D domain swapping / protein engineering / protein oligomerization / protein aggregation / amyloid

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