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TitleStructural basis for error-free replication of oxidatively damaged DNA by yeast DNA polymerase eta.
Journal, issue, pagesStructure, Vol. 18, Page 1463-1470, Year 2010
Publish dateAug 17, 2010 (structure data deposition date)
AuthorsSilverstein, T.D. / Jain, R. / Johnson, R.E. / Prakash, L. / Prakash, S. / Aggarwal, A.K.
External linksStructure / PubMed:21070945
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-3oha:
Yeast DNA polymerase eta inserting dCTP opposite an 8oxoG lesion
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-3ohb:
Yeast DNA polymerase eta extending from an 8-oxoG lesion
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-DCP:
2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE

ChemComp-SO4:
SULFATE ION

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • saccharomyces cerevisiae (brewer's yeast)
KeywordsTRANSFERASE/DNA / Protein-DNA complex / Nucleotidyltransferase / DNA-directed DNA polymerase / DNA replication / DNA repair / DNA binding / nucleotide binding / metal binding / Nucleus / TRANSFERASE-DNA complex / magnesium binding

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