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TitleStructure, Energetics and Dynamics of Binding Coactivator Peptide to Human Retinoid X Receptor Alpha Ligand Binding Domain Complex with 9-cis-Retinoic Acid.
Journal, issue, pagesBiochemistry, Vol. 50, Page 93-105, Year 2011
Publish dateAug 5, 2010 (structure data deposition date)
AuthorsXia, G. / Boerma, L.J. / Cox, B.D. / Qiu, C. / Kang, S. / Smith, C.D. / Renfrow, M.B. / Muccio, D.D.
External linksBiochemistry / PubMed:21049972
MethodsX-ray diffraction
Resolution2.05 Å
Structure data

PDB-3oap:
Crystal structure of human Retinoid X Receptor alpha-ligand binding domain complex with 9-cis retinoic acid and the coactivator peptide GRIP-1
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-9CR:
(9cis)-retinoic acid / anticancer, antineoplastic*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / antiparallel sandwich / ligand binding / coactivator binding / dimerization / activation function

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