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Structure paper

TitleCrystallographic complexes of surfactant protein A and carbohydrates reveal ligand-induced conformational change.
Journal, issue, pagesJ. Biol. Chem., Vol. 286, Page 757-765, Year 2011
Publish dateOct 19, 2010 (structure data deposition date)
AuthorsShang, F. / Rynkiewicz, M.J. / McCormack, F.X. / Wu, H. / Cafarella, T.M. / Head, J.F. / Seaton, B.A.
External linksJ. Biol. Chem. / PubMed:21047777
MethodsX-ray diffraction
Resolution1.8 - 2.3 Å
Structure data

PDB-3pak:
Crystal Structure of Rat Surfactant Protein A neck and carbohydrate recognition domain (NCRD) complexed with Mannose
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-3paq:
Surfactant Protein A neck and carbohydrate recognition domain (NCRD) complexed with alpha-methylmannose
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-3par:
Surfactant Protein-A neck and carbohydrate recognition domain (NCRD) in the absence of ligand
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3pbf:
Surfactant Protein-A neck and carbohydrate recognition domain (NCRD) complexed with glycerol
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-CA:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-MAN:
alpha-D-mannopyranose

ChemComp-HOH:
WATER

ChemComp-MMA:
methyl alpha-D-mannopyranoside

ChemComp-GOL:
GLYCEROL

Source
  • rattus norvegicus (Norway rat)
KeywordsSUGAR BINDING PROTEIN / collectin / mannose / carbohydrate binding / lectin

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