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TitleStructure of the Francisella tularensis enoyl-acyl carrier protein reductase (FabI) in complex with NAD(+) and triclosan.
Journal, issue, pagesActa Crystallogr. ,Sect. F, Vol. 66, Page 1436-1440, Year 2010
Publish dateJun 30, 2010 (structure data deposition date)
AuthorsMehboob, S. / Truong, K. / Santarsiero, B.D. / Johnson, M.E.
External linksActa Crystallogr. ,Sect. F / PubMed:21045289
MethodsX-ray diffraction
Resolution2.101 Å
Structure data

PDB-3nrc:
Crystal Structure of the Francisella tularensis enoyl-acyl carrier protein reductase (FabI) in complex with NAD+ and triclosan
Method: X-RAY DIFFRACTION / Resolution: 2.101 Å

Chemicals

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-TCL:
TRICLOSAN / antifungal, antibiotic, detergent*YM

ChemComp-HOH:
WATER

Source
  • francisella tularensis subsp. tularensis (bacteria)
KeywordsOXIDOREDUCTASE / Rossmann fold / enoyl-acyl carrier protein reductase / NADH binding

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