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Structure paper

TitleCrystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: comparison of native and antibiotic-bound forms
Journal, issue, pagesJ. Mol. Biol., Vol. 405, Page 173-184, Year 2011
Publish dateAug 9, 2010 (structure data deposition date)
AuthorsSainsbury, S. / Bird, L. / Rao, V. / Shepherd, S.M. / Stuart, D.I. / Hunter, W.N. / Owens, R.J. / Ren, J.
External linksJ. Mol. Biol. / PubMed:20974151
MethodsX-ray diffraction
Resolution1.968 - 2.61 Å
Structure data

PDB-3oc2:
Crystal structure of penicillin-binding protein 3 from Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION / Resolution: 1.968 Å

PDB-3ocl:
Crystal structure of penicillin-binding protein 3 from Pseudomonas aeruginosa in complex with carbenicillin
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3ocn:
Crystal structure of penicillin-binding protein 3 from Pseudomonas aeruginosa in complex with ceftazidime
Method: X-RAY DIFFRACTION / Resolution: 2.61 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-CB9:
(2R,4S)-2-[(1R)-1-{[(2S)-2-carboxy-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid

ChemComp-GOL:
GLYCEROL

ChemComp-CTJ:
1-({(2R)-2-[(1R)-1-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-2-oxoethyl]-4-carboxy-3,6-dihydro-2H-1,3-thiazin-5-yl}methyl)pyridinium

Source
  • pseudomonas aeruginosa (bacteria)
KeywordsPENICILLIN-BINDING PROTEIN / penicillin-binding proteins / Pseudomonas aeruginosa / Structural Genomics / Oxford Protein Production Facility / OPPF / transpeptidase / cell wall biosynthesis / out periplasmic membrane / PENICILLIN-BINDING PROTEIN/ANTIBIOTIC / carbenicillin / PENICILLIN-BINDING PROTEIN-ANTIBIOTIC complex / ceftazidime

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