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TitleStructure of the Mycobacterium tuberculosis D-Alanine:D-Alanine Ligase, a Target of the Antituberculosis Drug D-Cycloserine.
Journal, issue, pagesAntimicrob. Agents Chemother., Vol. 55, Page 291-301, Year 2011
Publish dateFeb 23, 2010 (structure data deposition date)
AuthorsBruning, J.B. / Murillo, A.C. / Chacon, O. / Barletta, R.G. / Sacchettini, J.C.
External linksAntimicrob. Agents Chemother. / PubMed:20956591
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-3lwb:
Crystal Structure of apo D-alanine:D-alanine Ligase (Ddl) from Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-NO3:
NITRATE ION

ChemComp-HOH:
WATER

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsLIGASE / D-alanine--D-alanine Ligase / Ddl / D-alanyl--D-alanine Ligase / Rv2981c / D-alanine / Structural Genomics / TB Structural Genomics Consortium / TBSGC / ATP-binding / Cell shape / Cell wall biogenesis / degradation / Magnesium / Manganese / Metal-binding / Nucleotide-binding / Peptidoglycan synthesis

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