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Structure paper

TitleStructural context shapes the aquaporin selectivity filter.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 107, Page 17164-17169, Year 2010
Publish dateJun 18, 2010 (structure data deposition date)
AuthorsSavage, D.F. / O'Connell, J.D. / Miercke, L.J. / Finer-Moore, J. / Stroud, R.M.
External linksProc. Natl. Acad. Sci. USA / PubMed:20855585
MethodsX-ray diffraction
Resolution2.4 - 3.1 Å
Structure data

PDB-3nk5:
Crystal structure of AqpZ mutant F43W
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-3nka:
Crystal structure of AqpZ H174G,T183F
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-3nkc:
Crystal structure of AqpZ F43W,H174G,T183F
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-BOG:
octyl beta-D-glucopyranoside / detergent*YM

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • escherichia coli (E. coli)
KeywordsTRANSPORT PROTEIN / aquaporin / integral membrane protein / selectivity filter / selectivity filter mutants

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