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TitleNovel immunodominant peptide presentation strategy: a featured HLA-A*2402-restricted cytotoxic T-lymphocyte epitope stabilized by intrachain hydrogen bonds from severe acute respiratory syndrome coronavirus nucleocapsid protein
Journal, issue, pagesJ. Virol., Vol. 84, Page 11849-11857, Year 2010
Publish dateJul 7, 2009 (structure data deposition date)
AuthorsLiu, J. / Wu, P. / Gao, F. / Qi, J. / Kawana-Tachikawa, A. / Xie, J. / Vavricka, C.J. / Iwamoto, A. / Li, T. / Gao, G.F.
External linksJ. Virol. / PubMed:20844028
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-3i6l:
Newly identified epitope N1 derived from SARS-CoV N protein complexed with HLA-A*2402
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • hcov-sars (virus)
KeywordsIMMUNE SYSTEM / HLA-A*2402 / SARS-CoV / nucleocapsid protein / Disulfide bond / Glycoprotein / Host-virus interaction / Immune response / Membrane / MHC I / Transmembrane / Disease mutation / Glycation / Immunoglobulin domain / Pyrrolidone carboxylic acid / Secreted / Golgi apparatus / Phosphoprotein / Ribonucleoprotein / RNA-binding / Viral nucleoprotein / Virion

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