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Structure paper

TitleStructural evidence for loose linkage between ligand binding and kinase activation in the epidermal growth factor receptor.
Journal, issue, pagesMol. Cell. Biol., Vol. 30, Page 5432-5443, Year 2010
Publish dateJun 17, 2010 (structure data deposition date)
AuthorsLu, C. / Mi, L.Z. / Grey, M.J. / Zhu, J. / Graef, E. / Yokoyama, S. / Springer, T.A.
External linksMol. Cell. Biol. / PubMed:20837704
MethodsX-ray diffraction
Resolution3.304 Å
Structure data

PDB-3njp:
The Extracellular and Transmembrane Domain Interfaces in Epidermal Growth Factor Receptor Signaling
Method: X-RAY DIFFRACTION / Resolution: 3.304 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-2PE:
NONAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / receptor tyrosine kinase

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