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-Structure paper
Title | Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: novel VEGFR2 kinase inhibitors binding to inactive kinase conformation. |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 18, Page 7260-7273, Year 2010 |
Publish date | Aug 24, 2011 (structure data deposition date) |
![]() | Oguro, Y. / Miyamoto, N. / Okada, K. / Takagi, T. / Iwata, H. / Awazu, Y. / Miki, H. / Hori, A. / Kamiyama, K. / Imamura, S. |
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Methods | X-ray diffraction |
Resolution | 1.55 Å |
Structure data | ![]() PDB-3vhe: |
Chemicals | ![]() ChemComp-42Q: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / KINASE DOMAIN / KINASE / TRANSFERASE-TRANSFERASE INHIBITOR complex |